San Francisco is home to Lefty's, opened in 1979 and the very first store to cater to left-handers in the United States. They also have a large number of items available for sale online.
I'm disappointed I wasn't aware that this store existed when I lived there! I'll definitely check it out when I am back in SF.
A limited number of items are available at the Lefty's kiosk in the Downtown Disney Marketplace in Orlando, Florida.
After checking out the left-handed store at Pier 39, if you're in need of some “adult only” entertainment, head over to Lefty O'Doul's in Union Square for a drink and to watch the game.
Opened in 1958, Lefty's is named after baseball pro and native San Franciscan Francis "Lefty" O'Doul and is the city's longest-standing sports bar - and may be the longest-standing sports bar in the country.